Journal: Frontiers in Aging
Article Title: The Usefulness of Radiomics Methodology for Developing Descriptive and Prognostic Image-Based Phenotyping in the Aging Population: Results From a Small Feasibility Study
doi: 10.3389/fragi.2022.853671
Figure Lengend Snippet: Mitochondrial radiomic signature of ultrasound images. Radiomics aims to capture the informative content hidden in medical images, overcoming the limitations of the human eyes and human cognitive patterns. These patterns can be expressed in terms of macroscopic image-based radiomic features and carry information about their underlying pathophysiological processes and pinpoint specific biological mechanisms. This allows us to infer phenotypes or signatures, including prognostic information. Here we graphically showed that a radiomic phenotype, capturing the muscle heterogeneity, was strongly prognostic of the development of hearing impairment, stroke, myocardial infarction, dementia/memory loss, and/or falls. Based on the type of disease associated with the muscle ultrasound changes, we also believe this identified group of diseases shares a mitochondrial link. Icons utilized in this figure were obtain from the Noun Project from the following authors: Gorkem Oner (mitochondria), Gregor Cresnar (ear), Artem Kovyazin (brain), Tatina Vazest (heart), Luis Padra (fading head) and Visual Language Company (slipping person).
Article Snippet: The features were extracted using the MATLAB toolbox Radiomics implemented by Vallières and others ( ).
Techniques: